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Nucleic Acid Purification

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Quality automated nucleic acid isolation with chemagic™ technology

Revvity provides a unique and efficient method for isolating nucleic acids based on chemagic technology established over 25 years. With our solution-oriented development that strives to put customers first, we offer high-quality instrumentation, proprietary M-PVA Magnetic Beads and separation technology to ensure consistent nucleic acid quality for all types of downstream applications. Our cross-functional application and automation teams ensure excellent support and a reliable supply of reagents to our customers.

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Discover our nucleic acid isolation solutions for research

m-pva magnetic beads

M-PVA Magnetic Beads

Our M-PVA magnetic beads are small iron oxide particles encapsulated in a matrix of polyvinyl alcohol. Their functional group defines their binding affinity to either nucleic acids, proteins or biomolecular molecules.
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chemagic Applications

Whether you’re handling one or multiple sample types in a single workflow, dealing with low or high sample volumes, or need specific extraction conditions, chemagic offers solutions tailored to your laboratory needs.
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chemagic nucleic acid purification kits

chemagic Kits

The chemagic™ Kits are specifically designed for use with chemagic automation, liquid handling instruments, and magnetic stands.
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chemagic instruments

chemagic Instruments

To achieve high nucleic acid integrity, the chemagic instruments employ the use of rotating magnetizable steel rods that automate resuspension of M-PVA Magnetic Beads for gentle yet efficient extraction of nucleic acids.
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For research use only. Not for use in diagnostic procedures.

Explore our clinical nucleic acid isolation solutions

chemagic-ivd-instruments512x288

chemagic IVD Instruments

chemagic IVD instruments deliver cutting-edge solutions for automated nucleic acid isolation, designed to meet the diverse needs of clinical diagnostic laboratories.
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chemagic-ivd-kits-thumbnail

chemagic IVD Kits

Revvity's chemagic IVD Kits offer state-of-the-art nucleic acid purification for clinical diagnostics and research. These kits are IVD marked and fully compliant with the European Union's In Vitro Diagnostic Medical Device Regulation 2017/746 (IVDR), ensuring reliability and regulatory conformity.
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For In Vitro Diagnostic Use. Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.

How it works?

The chemagic separation technology involves specific capture of nucleic acids by M-PVA Magnetic Beads that are attracted to transiently magnetized metal rods. The magnetized rods transfer the M-PVA Magnetic Beads through the different process solutions, avoiding potential sample cross-contamination. Rotation of the demagnetized rod heads efficiently resuspends the particles during washing steps. This generates high yields, purity, and low levels of fragmentation of nucleic acids, ensuring success in all types of downstream applications.

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Benefits of chemagic technology

Flexible and reliable extraction workflows

Sample volumes ranging from 50 µl to 18 ml with fast run times.

Proven performance in diverse assays

With diverse sample types, extraction targets, and downstream applications.

High purity and yields

Nucleic acids ready for downstream applications.

Unique separation method

Reduced risk of cross-contamination due to not transferring any liquid.

Quality automated DNA/RNA isolation

Efficient automated extraction of (HMW) DNA, RNA, cfDNA, miRNA.

Empower your research with our nucleic acid purification solutions.
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Featured resources

Webinar

Discover advanced high-throughput DNA extraction techniques for population studies

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Blog

From bottleneck to breakthrough: mastering automation in nucleic acid purification for the modern lab.

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Case study

Unlocking excellence in high-throughput nucleic acid extraction

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Blog

The critical importance of high molecular weight DNA for long-read sequencing.

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Blog

Tips on establishing a reliable cell free DNA (cfDNA) workflow from plasma samples.

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