NHS-activated M-PVA Magnetic Beads for easy protein immobilization

M-PVA Ak11 and Ak12 Magnetic Beads are coated with N-hydroxysuccinimide (NHS) functional groups. NHS groups are known for their ability to react with primary amines (-NH2) in proteins and other molecules forming stable amide linkages. This covalent binding is a robust and stable way to immobilize proteins onto the magnetic bead surface, which will not allow proteins easily detach or wash away during subsequent experimental steps.

Hydrophilic surface of M-PVA Ak11 and Ak12 Magnetic Beads will decrease the level of unspecific binding with other molecules to the minimum. Thanks to the robustness of the M-PVA structure, Ak11 and Ak12 Magnetic Beads can be used both manually with a magnetic stand or with automated platforms like chemagic 360 instrument.

Specifications

M-PVA Ak11 Magnetic Beads

• Product number: CMG-221
• Size: 0.6-1.25 µm
• Functionalization: > 650 µmol NHS/g M-PVA Ak11 Magnetic Beads
• Concentration: 25 mg/ml
• Unit size: 50 mg
• Storage: +2 to +8 °C

M-PVA Ak12 Magnetic Beads

• Product number: CMG-222
• Size: 0.8-3.0 µm
• Functionalization: > 550 µmol NHS/g M-PVA Ak12 Magnetic Beads
• Concentration: 25 mg/ml
• Unit size: 50 mg
• Storage: +2 to +8 °C

Quality

We are certified according to DIN EN ISO 9001:2015.

Workflow examples

1. Acharya G, Chang CL, Doorneweerd DD, Vlashi E, Henne WA, Hartmann LC, Low PS, Savran CA. Immunomagnetic diffractometry for detection of diagnostic serum markers. J Am Chem Soc. 2007 Dec 26;129(51):15824-9. 
2. Lee TJ, Zhang H, Chang CL, Savran C, Guo P. Engineering of the fluorescent-energy-conversion arm of phi29 DNA packaging motor for single-molecule studies. Small. 2009 Nov;5(21):2453-9.