DNA and RNA from saliva
Saliva has become an important source of nucleic acid material for human genetic testing. It is non-invasive, which makes it a preferred choice for individuals who dislike needles. The PerkinElmer chemagen solutions provide high yield and purity genomic DNA and total RNA from a minimal amount of sample. We observe high molecular weight gDNA and high integrity total RNA and they work with several downstream applications including sequencing (Next-Generation, Whole Genome, Whole Exome, Sanger, and long-read), quantitative PCR, and more.
- Manzoor, M., Lommi, S., Furuholm, J. et al. High abundance of sugar metabolisers in saliva of children with caries. Sci Rep 11,4424 (2021).
- Campuzano O, Sarquella-Brugada G, Fernandez-Falgueras A, Coll M, Iglesias A, Ferrer-Costa C, Cesar S, Arbelo E, García-Álvarez A, Jordà P, Toro R, Tiron de Llano C, Grassi S, Oliva A, Brugada J, Brugada R. Reanalysis and reclassification of rare genetic variants associated with inherited arrhythmogenic syndromes. EBioMedicine. (2020)
- Yao RA, Akinrinade O, Chaix M, Mital S. Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients. BMC Med Genomics. (2020)
- Senok, A., Alsuwaidi, H., Atrah, Y., Al Ayedi, O., Al Zahid, J., Han, A., Al Marzooqi, A., Al Heialy, S., Altrabulsi, B., AbdelWareth, L., Idaghdour, Y., Ali, R., Loney, T., & Alsheikh-Ali, A. . Saliva as an Alternative Specimen for Molecular COVID-19 Testing in Community Settings and Population-Based Screening. Infection and drug resistance, 13, 3393–3399. (2020)
For research use only. Not for use in diagnostic procedures.
Please note that product labelling (such as kit insert, product label, and kit box) may be different compared to the company branding. Please contact your local representative for further details.