M-PVA SAV Magnetic Beads

Streptavidin Magnetic Beads Einleitungstext

Higher binding capacity and consistent results with chemagic™ streptavidin coated magnetic beads

chemagic™ M-PVA Magnetic Beads functionalized with streptavidin are commonly used for the isolation of biotinylated target molecules, such as oligos, mRNA and proteins. Incorporating the outstanding properties of M-PVA Magnetic Beads, the streptavidin modified ones show a higher biotin binding capacity compared to competitors and are produced with stringent quality controls, ensuring good lot-to-lot conformity. chemagic M-PVA SAV Magnetic Beads can be used in diverse downstream applications including nucleic acid enrichment or depletion for NGS, immunoprecipitation, protein purification, enrichment of sample/cells/organelles, and more.

Streptavidin Magnetic Beads

M-PVA Magnetic Beads functionalized with streptavidin are commonly used for the isolation and handling of nucleic acids and biotinylated ligands and targets, including antigens and antibodies. Immobilized Streptavidin on the surface of the beads empower binding and immobilization of biotinylated target molecules, such as oligos, ssDNAs, proteins.

The binding capacity of biotinylated targets in water is generally 500 pmol/mg bead. Higher binding efficiency (800 pmol/mg bead) is achieved in the presence of our coupling buffer.

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Excited about testing our M-PVA SAV Magnetic Beads in your workflow? Then check out the available options on various size ranges and fill out the form below!

Sprungziel Specifications

Specifications M-PVA SAV Magnetic Beads

Specifications

Binding capacity

  • > 3000 pmol free biotin/mg M-PVA SAV Magnetic Beads (Figure 1)
  • > 800 pmol ssOligo/mg M-PVA SAV Magnetic Beads (Figure 2)
  • > 30 pmol biotinylated protein/mg M-PVA SAV Magnetic Beads
SAV Magnetic Beads Application data

Figure 1. M-PVA SAV1 Magnetic Beads binding capacity of free biotin compared to the competitor streptavidin coated magnetic beads.

SAV Bead Lot confirmity

Figure 2. Lot-to-lot conformity of M-PVA SAV1 Magnetic Beads by testing the binding capacity of biotinylated ssOligos.

Specifications M-PVA SAV Magnetic Beads

Size

Our M-PVA SAV Magnetic Beads are available in two different size ranges. SAV1 indicates that > 90.0 % of all particles are in the range of 0.60 – 1.25 µm. Whereas > 90.0 % of all SAV2 particles are in the range of 0.80 – 3.0 µm.

Magnetite Content

The high magnetite content of 50 – 60 % (total dry weight) ensures rapid magnetic separation in complex environments even with high volume.

Concentration

The standard concentration is 25 mg/ml, which can be customized upon the requirements of your workflow.

Storage conditions

  • Storage buffer: PBS Buffer (pH 7.0), 0.05% NaN3
  • Storage temperature: 2 – 8 °C
  • Shelf life: 24 months
  • Appearance: Brown suspension

Sprungziel Quality

Quality

Our M-PVA Magnetic Beads are produced in Germany for over 25 years with reliable quality and constant R&D efforts to support the increasing demands of our customers, and to develop new products to serve the needs of the fast-evolving biotech, pharma, and molecular diagnostics market.

We deliver reproducible binding capacities of > 800 pmol/mg M-PVA Magnetic Bead (M-PVA SAV1 Magnetic Beads, CMG-227) with excellent quality while maintaining an affordable price.

We are ISO 9001 certified supplier.

ParameterAcceptance criteria
Particle sizeM-PVA SAV1 Magnetic Beads > 90.0% of all particles in the range of 0.60 – 1.25 µm
M-PVA SAV2 Magnetic Beads > 90.0% of all particles in the range of 0.80 – 3.0 µm
Magnetite content50 - 60% of total dry weight
SterilityNo visible microorganism growth. Bacterial DNA free tested by 16S rDNA PCR
Binding properties> 30 pmol biot. protein per mg

Sprungziel Workflows

Workflows with SAV Magnetic Beads

Workflows with SAV M-PVA Magnetic Beads

Effective ribosomal RNA Depletion using Revvity´s Hybridization Technology

The Nextflex® Ribonaut™ rRNA Depletion Kit is used to deplete ribosomal RNA while preserving other RNA species. The subtractive hybridization technology uses biotinylated oligos to selectively capture rRNAs and remove them from the sample using streptavidin coated M-PVA Magnetic Beads.

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Sprungziel Products

Product Overview M-PVA SAV Magnetic Beads

M-PVA SAV Magnetic Beads

Product No.NameFunctionalizationSize
[µm]
Conc.
[mg/ml]
CMG-227M-PVA SAV1 Magnetic BeadsStreptavidin0.60 - 1.2525
CMG-228M-PVA SAV2 Magnetic BeadsStreptavidin0.8 - 3.025

Product Overview M-PVA SAV Magnetic Beads

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    RNA productionVaccine productionAssay developmentNucleic acid isolationProtein purificationResearch and developmentPharmaBiotechnologyOther

    For research use only. Not for use in diagnostic procedures.