Carboxylated M-PVA Magnetic Beads for easy coupling of diverse molecules

Carboxylated M-PVA Magnetic Beads contain carboxyl (COOH) functional groups on the surface, which allows for easy and controlled coupling of various molecules, including proteins, nucleic acids, or other amino ligands. M-PVA Magnetic Beads are made from a matrix of polyvinyl alcohol (PVA). This material provides a stable and inert structure for the beads, allowing for further functionalization and use in various applications.

The high content of magnetite in our carboxylated beads gives them superparamagnetic properties. This means that the beads become magnetized when exposed to a magnetic field but lose their magnetization once the field is removed, making them compatible with the automated magnetic separation platforms such as chemagic 360 or chemagic Prime instrument for rapid separation processes, even in complex environments with high volume.

Specifications

M-PVA C11 Magnetic Beads

• Product number: CMG-203
• Size: 0.6-1.25 µm
• Functionalization: > 600 µmol carboxyl groups/g M-PVA C11 Magnetic Beads
• Concentration: 50 mg/ml
• Unit size: 500 mg
• Storage: +2 to +25 °C

M-PVA C21 Magnetic Beads

• Product number: CMG-206
• Size: 0.6-1.25 µm
• Functionalization: > 950 µmol carboxyl groups/g M-PVA C21 Magnetic Beads
• Concentration: 50 mg/ml
• Unit size: 500 mg
• Storage: +2 to +25 °C

M-PVA C22 Magnetic Beads

• Product number: CMG-207
• Size: 0.8-3.0 µm
• Functionalization: > 950 µmol carboxyl groups/g M-PVA C22 Magnetic Beads
• Concentration: 50 mg/ml
• Unit size: 500 mg
• Storage: +2 to +25 °C

Quality

We are certified according to DIN EN ISO 9001:2015.

 

Workflow examples

1. Perez-Perri JI, Ferring-Appel D, Huppertz I, et al. The RNA-binding protein landscapes differ between mammalian organs and cultured cells. Nat Commun. 2023;14(1):2074. Published 2023 Apr 12.
2. Perez-Perri JI, Noerenberg M, Kamel W, et al. Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture. Nat Protoc. 2021;16(1):27-60.
3. Deraney RN, Troiano D, Joseph R, Sam SS, Caliendo AM, Tripathi A. Vortex- and Centrifugation-Free Extraction of HIV-1 RNA. Mol Diagn Ther. 2019 Jun;23(3):419-427. 
4. P. J. Petrino, Y. H. Gaston-Bonhomme, and J. L. E. Chevalier. Viscosity and Density of Binary Liquid Mixtures of Hydrocarbons, Esters, Ketones, and Normal Chloroalkanes. Journal of Chemical  Engineering Data 1995 40 (1), 136-140
5. Ferner, Marvin & Müller, Gabi & Schumann, Christiane & Kampeis, Percy & Ulber, Roland & Raddatz, Heike. Immobilisation of glycosidases from commercial preparation on magnetic beads. Part 1. Characterisation of immobilised glycosidases with a particular emphasis on β-glucosidase. Journal of Molecular Catalysis B: Enzymatic. 2015.