Oligo (dT) coated M-PVA Magnetic Beads to empower your nucleic acid coupling

Experience the pinnacle of magnetic particle technology with chemagic M-PVA OdT2 Magnetic Beads to empower your nucleic acid coupling. Crafted through our proprietary Revvity chemagen technology, these beads feature superparamagnetic properties and a hydrophilic polyvinyl alcohol surfacewith covalently immobilized Oligo(dT)30, available as M-PVA OdT2 Magnetic Beads.

What sets our M-PVA OdT2 Magnetic Beads apart is their high magnetite content (50-60 % of total dry weight), ensuring rapid magnetic separation even when dealing with sizable sample volumes. Sized at 0.8-3.0 µm, these micrometer-scale beads boast a high surface per volume, adaptable to a diverse range of applications.

M-PVA OdT2 Magnetic Beads are defined by their hydrophilic polyvinyl alcohol matrix, effectively minimizing unspecific binding. The robust mechanical nature of the M-PVA OdT2 Magnetic Beads grants them versatility, making them an ideal choice for various processing methods, including automation. M­ PVA OdT2 Magnetic Beads are commonly used for coupling of poly-adenylated nucleic acids, with a guaranteed yield of >45 pmol dA30. This makes them the ideal candidate for mRNA isolation and purification. The pure mRNAs could be then used for cDNA synthesis, library preparation, or any other mRNA based methods.

Specifications

M-PVA OdT2 Magnetic Beads

• Product number: CMG-231
• Size: 0.8-3.0 µm
• Yield: >45 nmol Oligo(dA)30/g M-PVA OdT2
• Concentration: 25 mg/ml
• Unit size: 50 mg
• Storage: 2-8 °C

Other specifications on demand.

Quality

We are certified according to DIN EN ISO 9001:2015.

Workflow examples

Ready to use for capturing of intact mRNA.

1. Berensmeier S. Magnetic particles for the separation and purification of nucleic acids. Appl Microbiol Biotechnol. 2006 Dec;73(3):495-504. 
2. Becker W, Kluge R, Kantner T, Linnartz K, Korn M, Tschank G, Plum L, Giesen K, Joost HG. Differential hepatic gene expression in a polygenic mouse model with insulin resistance and hyperglycemia: evidence for a combined transcriptional dysregulation of gluconeogenesis and fatty acid synthesis. J Mol Endocrinol. 2004 Feb;32(1):195-208.